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When to wait before testing?

  1. Post-Surgery Period: It's advisable to avoid testing immediately after surgery. Surgical procedures can cause significant physiological stress and immune response alterations, which could temporarily affect glycans' profiles on IgG.
  2. During or Immediately After Severe Infections: This includes specific viruses like COVID-19. Viral infections, especially severe ones, can cause acute inflammatory responses and immune system alterations, leading to temporary changes in glycan structures.
    1. Q : I’ve had Covid, can I take the test now? A: Only really severe cases of covid change one's glycan profile, so if in this person's case it was a simple cold, there should be no interference with the results
  3. During Acute Illnesses or Flare-ups of Chronic Conditions: For patients with chronic illnesses, it's important to test during a stable phase rather than during a flare-up. Acute illnesses can also cause temporary inflammatory responses, skewing the results. **Note however that minor viral infections do not affect GlycanAge.
  4. Post-Vaccination Period: It may be beneficial to wait a certain period after vaccination before testing. Vaccines stimulate the immune system and can temporarily alter IgG glycosylation.
  5. During High-Stress Periods: Significant physical or emotional stress can impact the immune system and might affect glycan profiles. If a patient is going through a particularly stressful period, it might be better to wait until they are in a more stable state.
  6. Pregnancy: Pregnancy significantly alters the immune system and hormonal balance, which can affect glycan patterns. Testing during pregnancy may not reflect the individual's typical glycan profile.
    1. So ideally, in pregnancy you'll get a better GlycanAge than her actual one, and postpartum she'll get a worse one. The best recommendation is to test 6 months after your menstrual cycle is stable again. Please let me know if that helps.
  7. Recent Changes in Medication: Certain medications, especially those affecting the immune system or inflammation (like steroids), can alter glycan patterns. It's important to consider the timing of such medication changes when planning the test.
  8. Q: I am a Type 2 Diabetic and my blood sugars are still very high. Can I take the test?
    A: Would be best to test whenever your glucose goes back into range that is normal for you.
  9. Q: I had plasma exchange therapy/plasmapheresis treatment around 5 weeks ago. Will this impact my results?
    A: It can show how this intervention has affected the levels of chronic inflammation in his body. We usually recommend at least six weeks from an intervention to measure the effects of it so your boss should be good to test in a week’s time.