How does GlycanAge differ from classical inflammatory biomarkers such as CRP and IL-6?

Classical inflammatory biomarkers such as CRP and IL-6 are useful for detecting acute or short-term inflammation, but they are not designed to measure immune aging. These markers can change quickly in response to factors such as infection, intense exercise, poor sleep, or other temporary physiological stressors, which makes them less suitable for assessing longer-term patterns.

GlycanAge takes a different approach. By measuring changes in IgG glycosylation, it reflects cumulative immune system behavior over the past few months rather than short-lived inflammatory events. This makes it particularly useful for assessing chronic, low-grade inflammation and tracking broader patterns related to immune aging over time.